BotDB - BoNT inhibitor summary

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BoNT Candidate Inhibitors

As research in BoNT candidate inhibitors continues to expand, BotDB candidate inhibitor database is also expected to grow. Search or view inhibitors in BotDB database using different fields: author name, IC₅₀, inhibition site, inhibitor type, K_i, inhibitor name, PMID, serotype and structure.
Note
In cases where a candidate inhibitor exhibits inhibition on more than one serotype, it will be displayed more than once in the result page. For instance, 3,4-DAP exhibits inhibition on serotypes A, B, C1, and E and therefore will be displayed four times on the result page.

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Hide summary tables

Type	Count
Synthetic	34
Peptide	27
Natural Compound	2
Monoclonal Antibody	6

Serotype	Count
BoNT A	60
BoNT B	7
BoNT E	2
BoNT C1	1
BoNT F	6

Reference	Count
Schmidt JJ et al., 1998	16
Lundh H et al., 1977	3
Simpson LL, 1988	4
Burnett JC et al., 2007	4
Kumaran D et al., 2008	4
Anne C et al., 2003	1
Eubanks LM et al., 2007	12
Shi YL and Li MF, 2007	3
Silvaggi NR et al., 2008	1
Adler M et al., 1998	1
Tang J et al., 2007	2
Burnett JC et al., 2003	9
Schmidt JJ and RG Stafford, 2005	6
Amersdorfer P et al., 2002	6
Silvaggi NR et al., 2007	3
Eswaramoorthy S et al., 2002	1

Sponsored by U. S. Army Medical Research Institute of Infectious Diseases (USAMRIID) in collaboration with the National Cancer Institute (NCI) and Advanced Biomedical Computing Center (ABCC).Support for this project was provided by the Defense Threat Reduction Agency Joint Science and Technology Office-Chemical Biological defense (DTRA JSTO-CBD) project 3.10043_07_RD_B and by the National Cancer Institute, National Institutes of Health, under contract No. HHSN261200800001E.

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